Multidimensional nuclear magnetic resonance methods for protein studies
نویسنده
چکیده
Nuclear magnetic resonance (NMR) technology has advanced significantly over the past few years. After the initial development of threeand four-dimensional NMR spectroscopy, several important improvements on these experiments have been made; these offer significantly higher sensitivity and improved resolution, resulting in additional structural constraints. Other methodological improvements now make it possible to obtain complete resonance assignments, even in partially denatured proteins, opening new windows for studying the protein folding problem.
منابع مشابه
Multidimensional NMR methods for protein structure determination.
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تاریخ انتشار 2004